Authors: F. Alali, I. Karampelas, Y.H. Kim, E.P. Furlani
Affilation: University at Buffalo, United States
Pages: 41 - 44
Keywords: localized surface plasmon resonance (LSPR), photothermal cancer therapy, photothermal energy conversion, plasmonic-enhanced photothermal energy transfer, LSPR-induced optical absorption, pulsed-laser photothermal therapy
The ability to control the generation and transport of thermal energy with precision at the nanoscale has drawn increased interest in recent years, especially for emerging applications in fields such as nanoparticle synthesis, imaging and medical therapy, among others. Laser-based plasmon-enhanced photothermal energy conversion is of particular interest as it can provide efficient heating with unprecedented spatial resolution. In this approach, a pulsed laser is used to heat metalic nanostructures at their plasmon resonant frequency, which results in a peak absorption of incident photons and highly localized field enhancement. In addition to enabling efficient nanoscale heating from a remote source, the optimal (resonant) heating wavelength can be tuned within the ultraviolet through near-infrared spectrum. In this presentation, we discuss fundamental aspects of plasmon-enhanced photothermal heating along with applications. We use computational models to demonstrate key photothermal effects associated with nanosecond-pulsed, laser-heated colloidal metallic nanoparticles. We consider various nanoparticle geometries including spheres, rods and tori. We show that process parameters such as the laser intensity, incident wavelength, pulse duration and the orientation and shape of the nanoparticles can be tuned to optimize the phothermal process. We discuss the application of photothermal therapy to the destruction of cancer cells.
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