Nanotech 2010 Vol. 3
Nanotech 2010 Vol. 3
Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy

Cancer Nanotechnology Chapter 6

Bioluminescent Model for the Quantification of Photothermal Ablative Breast Cancer Therapy Mediated by Near-Infrared Nanoparticles

Authors: L.G. Gutwein, A.K. Singh, M.A. Hahn, M.C. Rule, S.C. Brown, B. Moudgil, S.R. Grobmyer

Affilation: University of Florida, United States

Pages: 386 - 389

Keywords: nanoparticles, bioluminescence, photothermal ablation, breast cancer

Multifunctional nanoparticles hold promise for enabling non-invasive image guided cancer therapy such as photothermal therapy. Human breast tumor models in which response to image guided therapy can quickly and non-invasively be determined are needed to facilitate translation and application of these technologies. We have developed a murine model capable of investigating the effects of photothermal ablative therapy and the fate of nanomaterials following photothermal therapy. The findings suggest the potential for a new paradigm for non-invasive breast cancer therapy.

ISBN: 978-1-4398-3415-2
Pages: 880
Hardcopy: $189.95