Nanotech 2008 Vol. 3
Nanotech 2008 Vol. 3
Nanotechnology 2008: Microsystems, Photonics, Sensors, Fluidics, Modeling, and Simulation - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 3

Lab-on-a-Chip, Micro & Nano Fluidics Chapter 3

Numerical Analysis of Nanofluidic Sample Preconcentration in Hydrodynamic Flow

Authors: Y. Wang, K. Pant, W. Diffey, Z. Chen, S. Sundaram

Affilation: CFD Research Corporation, United States

Pages: 442 - 445

Keywords: streaming potential, nanofluidic, electric double layer, preconcentration

This paper presents the first, high-fidelity numerical study of nanofluidic streaming potential-based sample preconcentration. Parametric analysis is performed to capture the critical effects of pressure and background electrolyte (BGE) concentration on preconcentrator performance. Our studies demonstrate that ion-polarization and electric field barrier can be established at micro-nano-channel interfaces and substantial sample enrichment (>10,000-fold) can be readily achieved using hydrodynamic flow. The results can be used for practical design and operational protocol development for novel sample preconcentrators.

ISBN: 978-1-4200-8505-1
Pages: 940
Hardcopy: $159.95