Moore A.C., Kolokoltsov A.A., Davey R.A.
University of Texas Medical Branch, US
Keywords: cell targeting, drug delivery, membrane penetration, virus
We build on our recently reported work in Nano letters describing coating of nanoparticle cargoes with virus envelope proteins to show that the method works for viruses other than ecotropic murine leukemia viruses. We also track the virus-envelope coated nanoparticles into cells using real-time microscopy on live cells. We discuss the potential benefits of using this method to target drugs to specific cells and subcellular compartments.
Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 20, 2007
Pages: 370 - 373
Industry sector: Medical & Biotech
Topics: Biomaterials, Materials for Drug & Gene Delivery
ISBN: 1-4200-6183-6