Papers:
Nanomedicine: Engineering of a Tri-Imageable Nanoparticle
Bumb A., Brechbiel M.W., Choyke P., Fugger L., Dobson P.J., National Cancer Instiute and University of Oxford, UK
We have created a potential targeted drug delivery platform with three imaging reporters by coupling the magnetic properties of USPIOs with near infrared fluorescence of Cy5.5 and gamma emissions of Indium-111 that is chelated to [...]
Optimizing Quantum Dot-Conjugated Immunoliposomes for Cancer Diagnostics and Targeted Therapeutics
Weng K.C., Noble C.O., Papahadjopoulos-Sternberg B., Chen F.F., Park J.W., UCSF Comprehensive Cancer Center, US
A multifunctional nanoparticle that combines the optical properties of luminescent quantum dots (QDs) and therapeutic modality of immunoliposomes (ILs) has been developed. Carboxylate-derivatized QDs cross-linked with amino- poly(ethylene glycol)-functionalized liposomes were modified with anti-human epidermal [...]
Using Electron Tunneling for Direct Sequencing of DNA
Genomic information has assumed a central role in the way biology in general and cell function in particular are understood today. Methods that can sequence DNA rapidly, accurately, and cost-effectively are needed in order to [...]
Nano Neuro Knitting: using nanotechnology to repair the brain
Ellis-Behnke R.G., Liang Y-X, You S-W, Tay D.K.C., Zhang S., So K-F, Schneider G.E., Massachusetts Institute of Technology, US
Nanotechnology is often associated with materials fabrication, microelectronics, and microfluidics; using nanotechnology and molecular self-assembly in biomedicine to repair injured brain structures had never been explored. To achieve axonal regeneration after injury in the CNS, [...]
Automated 3D cortex image data acquisition
The study of the 3D architecture of cortex tissue requires the creation of image data sets with sufficient detail in all directions. The detail level required to produce meaningful data requires imaging quality that allows [...]
Developing Super-Paramagnetic Nanoparticles for Central Nervous System Axon Regeneration
Neurons in the central nervous system (CNS) fail to regenerate their axons after injury or in degenerative disease, and stimulating regenerative growth remains a major goal of neuroscience. Mechanical tension plays a key role in [...]
Nanowire Array Technologies for Investigation of Neural Activity
Nanostructures are expected to play a key role in the fundamental investigation of neuronal activity at the nanoscale level. Neurons are complex structures with feature sizes ranging from the millimeter to micron to nanoscale regimes. [...]
Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 20, 2007
Industry sector: Medical & Biotech
Topics: Biomaterials, Cancer Nanotechnology
ISBN: 1-4200-6183-6