Papers:
Modeling of Cellular Communication
Barjis I., Barjis J., Samarrai W., Augustin I., Barjis I., Barjis J., New York City College of Technology, US
This paper introduces application of Rule based to molecular biology. In particular, it illustrates how by means of rule based the process of cellular communication can be modeled, and analyzed, where the model could be [...]
Molecular Dynamics Simulation of a Single Stranded (ss) DNA
The objective of this study was to develop an understanding of the essential physical properties of short-single stranded DNA (ssDNA) towards the development of new DNA based biosensors. To achieve this goal, various thermodynamic properties [...]
Computational Proof-of-Concept of Next-Generation Nucleotide–Tunneling-Current-Based Nanopore Sequencing Devices
A complete knowledge of the DNA sequence of an individual can yield fundamental insight into disease diagnosis, treatment and possibly prevention. To date the most reliable method of determining a genetic sequence is through the [...]
A Simple Surface Representation Scheme for Rigid Body Docking
In this paper, a new approach is proposed for modeling the surface patches of protein molecules for rigid body docking. The scheme presented in this paper for surface representation is simple and efficient. The proposed [...]
Fast Density-Functional-Theory Calculation With Q-Chem Program
DFT (Density functional Theory) is an essential tool in the molecular modeling, especially for studies in biology and nanotechnology. A new algorithm is presented to improve the efficiency of the computation of exchange-correlation contributions, a [...]
Investigation of the ssDNA Backbone Molecule Mechanical Behavior Using Atomistic-Continuum Mechanics Method
Han C-N, Chou C.Y., Wu C-J, Chiang K.N., Advanced Microsystem Packaging and Nano-Mechanics Research Laboratory, National Tsing Hua University, TW
As is known, various important physiological functions and gene engineering processes, such as RNA transcription/DNA replication/DNA repair, involve specific bio-physical mechanics of DNA. Therefore, in this study, a novel single-stranded DNA (ssDNA) model based on [...]
Entropy-Enhanced Genome Analysis in Frequency Domain
In this paper, we report the application of an entropy-enhanced frequency-domain analysis concept to examine large-scale genomic data. This ensures superior coherency for qualitative and quantitative analysis. Different statistical methods are used in order to [...]
DNA Translocation through a Nanopore
We are developing a technique to sequence the DNA with atomic force microsope. A single strand DNA is threaded to cyclodexrn ring and different forces are abserved as purine and oyrimidin pass through the ring. [...]
Modelling the Microscopic Mechanisms of Sonoporation
This work constitutes a theoretical follow up to our earlier paper in Nature Physics (November 2005) in which we demonstrate that, in the high amplutude limit, ultrasound stimulated microbubble cavitation behaviour can be approximated without [...]
In Silico Modification of Thermostable Lipase From Geobacillus sp. Strain T1
Rahman M.B.A., Rahman R.N.Z.A., Khan C.K., Basri M., Salleh A.B., Rahman M.B.A., Rahman R.N.Z.A., Universiti Putra Malaysia, MY
Protein cavities provide binding sites for biomolecular interaction with chemical ligands and metals. Interaction specificities and physical properties characterization of protein cavities as binding sites is the initial platform to design a semisynthetic metalloenzyme for [...]
Symmetry Dynamics in Leadership and Management
A symmetry model based on Molecular Orbital symmetry of neurotransmitters and their interaction with ion channeling effect is proposed in order to relate thiniking coordination patterns to leadership and management conditions and how can they [...]
Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2006 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 7, 2006
Industry sector: Medical & Biotech
Topics: Biomaterials, Informatics, Modeling & Simulation
ISBN: 0-9767985-7-3