Applications of Dielectrophoretic / electrohydrodynamic electrodes for concentration of biological nanoparticles

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Dielectrophoresis (DEP) is a phemomenon of induced particle motion in non-uniform electric fields. The effect is frequency dependent; by monitoring the motion of particles in AC fields and ananlysing the change in motion with frequency, it is possible to determine the electrical properties of single cells in lab-on-a-chip systems. By combining two common electrokinetic phenomena – dielectrophoresis and electrohydrodynamic fluid flow – we demonstrate that it is possible to manipulate, concentrate and trap particles from cell to molecular scale, and show how the trappig phenomenon is not related to particle size. We also discuss application of the phenomenon, from particle preconcentration in sensor systms to the deposition of particles on sensor surfaces.

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Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2006 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 7, 2006
Pages: 275 - 277
Industry sectors: Medical & Biotech | Sensors, MEMS, Electronics
Topics: Chemical, Physical & Bio-Sensors, Diagnostics & Bioimaging
ISBN: 0-9767985-7-3