NSTI Nanotech 2009

Action of Paclitaxel pH-Sensitive Liposomes on B16F1 Melanoma Cells

H. Karanth, R.S.R. Murthy
The M.S. University Of Baroda, IN

Keywords: liposomes, pH-sensitive, Melanoma, in-vitro release


Long circulating pH-sensitive liposomes loaded with Paclitaxel were developed and characterized for the encapsulation efficiency, release characteristics and its action on B16F1 melanoma cells (low metastatic). Paclitaxel loaded pH-sensitive liposomes showed better release pattern and promising in-vitro anticancer activity.
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