2008 NSTI Nanotechnology Conference and Trade Show - Nanotech 2008 - 11th Annual

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TechConnect Summit
Clean Technology 2008

Upconverting nanoparticles for in vitro and in vivo cellular imaging

D.K. Chatterjee, Y. Zhang
National University of Singapore, SG

nanoparticles, upconversion, fluorescence, imaging probes

Conventional fluorescent labels are of limited in vivo utility because short-wavelength radiation penetrates tissues poorly and excites strong background autofluorescence. Upconversion nanoparticles (UCN) convert low-energy exciting photons to visible emissions, resulting in deep tissue penetration and high detection sensitivity in vivo. Here, we report the synthesis and characterization of fluorescent UCN and demonstrate their use in molecular imaging in vitro and in vivo in small animals.

Nanotech 2008 Conference Program Abstract