2008 NSTI Nanotechnology Conference and Trade Show - Nanotech 2008 - 11th Annual

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TechConnect Summit
Clean Technology 2008

Preparation of gold-conjugated nanoparticle using food-grade materials for in vivo tracking

S. Ko, K.H. Kim, H.S. Chun
Sejong University, KR

gold nanoparticle, nanoencapsulation, food, in vivo tracking

Nanotechnology has been introduced into several aspects of food industry including encapsulations and delivery systems which protect and deliver functional food ingredients. Nanosized functional ingredients may be incorporated into some forms of delivery systems including nanodispersions, nanocapsules, and nanoparticles. Food-grade materials generally recognized as safe, biocompatible and biodegradable have the potential to be used for the delivery systems in a wide variety of foods. However, food-originated nanoencapsulated delivery systems may or may not have the toxicity since the physical, chemical, and biological properties of materials at the nanoscale differ in fundamental ways from the macro matter. Thus, the toxicological profiles of the nanosized delivery systems should be considered prior to human consumption. In the experiments, protein- and polysaccharide-originated nanoparticles were prepared to study their toxicity after oral administration. In order to track the nanoparticles in vivo, nanosized-gold colloids were conjugated into the nanoparticles. These gold-conjugated nanoparticles have the potential to study the fate of the nanoparticles in the biological systems. Our study may provide basic data to establish the procedure for evaluating the safety of the nanosized foods.

Nanotech 2008 Conference Program Abstract