2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

2D and 3D Nanostructured Amphiphile Self-Assembly Materials

C.J. Drummond, C. Fong, T. Kaasgaard, S. Sagnella, C. Conn, T. Greaves, I. Krodkiewska, A. Weerawardena and N. Gong

amphiphile self-assembly, nanostructured material

Amphiphile lyotropic liquid crystalline self assembly materials are being used for a diverse range of applications. Historically, the most studied lyotropic liquid crystalline phase is probably the 1-dimensional (1D) lamellar phase, which has been employed as a model system for biomembranes and for drug delivery applications. In recent years, the structurally more complex 2D and 3D ordered lyotropic liquid crystalline phases, of which reversed hexagonal (H2) and reversed cubic phases (V2) are two prominent examples, have received growing interest. As is the case for the lamellar phase, these phases are frequently stable in excess water, which facilitates the preparation of nanoparticle dispersions and makes them suitable for the encapsulation and controlled release of drugs. Integral membrane protein crystallization media and templates for the synthesis of inorganic nanostructured materials are other applications for 2D and 3D amphiphile self assembly materials. The number of amphiphiles identified as forming nanostructured reversed phases stable in excess solvent is rapidly growing. In this paper, a number of new amphiphiles that form reversed phases in excess solvent are reported, with an emphasis on linking phase behavior to amphiphile structure.

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Nanotech 2007 Conference Program Abstract


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