2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

Quantum Dot Labeling of Retinal Tissue Sections

C.W. Sharp, S. Pathak, M. Davidson and G.A. Silva
Univeristy of California, San Diego, US

QDot, astrocyte, reactive gliosis, retina

Quantum dot labeling is a new tool of significant potential for neuroscience research and may have unique applications for studying reactive gliosis, a ubiquitous neuropathological process. Since quantum dots exhibit stable fluorescent optical properties and can be attached to different proteins expressed by cells within the nervous system, they provide a promising alternative to traditional immunocytochemistry techniques for studying and imaging the anatomy and histology of the retina. By labeling retinal tissue sections (~5 um thick) with quantum dots, we have been able to explore the interactions between different cell types in the retina, including glial cells, in detail with high spatial resolution.

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Nanotech 2007 Conference Program Abstract


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