2007 NSTI Nanotechnology Conference and Trade Show - Nanotech 2007 - 10th Annual

Degradable polymeric nanowire arrays: biointerfaces for cellular control and sustained release

S.L. Tao and T.A. Desai

nanowire, PCL, biodegradable, drug delivery

Nanostructured materials for applications in biology and medicine have gained interest with recent findings that cellular responses can be directed by nanotopography. Here the simple method of template synthesis[1,2] is used to create arrays of free-standing nanowires and flexible nanofibers from the biocompatible, biodegradable polymer poly( -caprolactone) (PCL). It is shown that nanostructure morphology can be controlled and complex patterning may be achieved. Furthermore, sustained release of therapeutics can be delivered by the nanowires, and cellular interactions can be controlled.

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Nanotech 2007 Conference Program Abstract


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