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696 San Ramon Valley Blvd., Ste. 423
Danville, CA 94526
Ph: (925) 353-5004
Fx: (925) 886-8461

Fundamentals and Applications of
Micro, Bio and Nano Fluidics

micro bio nano fluidics

This short course will start with a consideration of the fundamentals of intermolecular forces and proceed to a consideration of where continuum assumptions are valid and where they are not. Scaling phenomena will be discussed, i.e. the importance of surface tension and dominance of drag, in continuous flows. The breakdown of continuum behavior will then be discussed and the utility of computational simulations outlined. A short introduction to electrokinetics will be provided. Then experimental techniques suitable for micro/nano flows will be presented. Finally aero-based examples will be discussed.

The short course will encompass issues ranging from nanotechnolgy to microsystems technologies (MEMS).

Course Instructor

Steve Wereley

Steven T. Wereley, Assistant Professor of mechanical engineering at Purdue University. He received his M.S. and Ph.D. in mechanical engineering from Northwestern University. His research interests line in Micro and Nanoscale fluid mechanics (microfluidics), MEMS, bio-MEMS, turbulence in microscopic domains, biological flows at the cellular level, micro-scale laminar mixing, development of microfluidic diagnostic techniques.


    fluid mechanics microfluidics
  1. Fluid mechanics theory in small but continuous flows
  2. Sub continuum fluids theory
  3. Electrokinetics
  4. Microscale experimental diagnostics
  5. Aero applications of microfluidics


  1. Introduction
    • Intermolecular Forces
    • The Three States of Matter
    • Continuum Assumption
  2. Continuum Fluid Mechanics at Small Scales
    • Boundary Conditions
    • Low Reynolds Number Flows
    • Surface Tension
  3. Molecular Approaches
    • Molecular Dynamics simulations
    • Direct Simulation Monte Carlo Technique
    electrokinetics, electrophoresis, electroosmosis, dielectrophoresis
  4. Electrokinetics(Electro-Osmosis, Electrophoresis, Dielectrophoresis)
  5. Experimental Flow Characterization
    • Pointwise Methods
    • Full-Field Methods
  6. Overview of Micro-PIV
    • Fundamental Physics Considerations of Micro-PIV
    • Extensions of the Micro-PIV technique
      • Microfluidic Nanoscope
      • Micro particle Image Thermometry
      • Infrared Micro-PIV
      • Particle Tracking Velocimetry
    microchannel flow, and micronozzles in biochops
  7. Application Examples
    • Flow in a Microchannel
    • Flow in a Micronozzle
    • Flow Around a Blood Cell
    • Flow in Microfluidic Biochip

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