Nano Science and Technology InstituteNano Science and Technology Institute
Nano Science and Technology Institute 2005 NSTI Nanotechnology Conference & Trade Show
Nanotech 2005
Bio Nano 2005
Business & Investment
Nano Impact Workshop
Index of Authors
Index of Keywords
Keynote Presentations
Confirmed Speakers
Participating Companies
Industry Focus Sessions
Nanotech Expo
Special Symposia
Venue 2005
Press Room
Site Map
Nanotech 2005 At A Glance
Nanotech Proceedings
Nanotechnology Proceedings
Global Partner
nano tech
Supporting Organizations
Nanotech 2005 Supporting Organization
Media Sponsors
Nanotech 2005 Medias Sponsors
Event Contact
696 San Ramon Valley Blvd., Ste. 423
Danville, CA 94526
Ph: (925) 353-5004
Fx: (925) 886-8461

Preparation of Zeolite Microspheres and their Application in Biology

L.W. Wong and K.L. Yeung
the Hong Kong University of Science and Technology, CN

zeolite microspheres, chemical storage, locally deliver

The potential use of zeolite hollow microspheres in biological studies was illustrated in the study of formation of neuromuscular junction (NMJ). The hollow zeolite microspheres carry and locally deliver signalling molecules, thus mimicking the in vivo signalling process between neurons and muscle bundle that lead to the formation of neuromuscular junction. The zeolite hollow microspheres were loaded with sodium pervanadate (i.e., Na-orthovanadate + H2O2), a known inhibitor of tyrosine phosphatase (PTPase) that regulates the MuSK activation needed to initiate the AChR clustering that prelude the formation of the neuromuscular junction. The zeolite microspheres were applied on Madin-Darby canine kidney (MDCK) as shown in Figure 2. The marker used to assess the action of the pervanadate PTPase inhibitor was anti-phosphotyrosine antibody. This indicated that the kinase activity is elevated at the microsphere-cell contact (Fig. 2). An understanding of the signalling process and post-synaptic formation of NMJ is critical to combating many serious diseases such as NMJ disorder, muscular dystrophy and Myasthenia Gravis. It may also provide insights in curing botulism and snakebite that act on NMJ.

Back to Program

Sessions Sunday Monday Tuesday Wednesday Thursday Authors

Nanotech 2005 Conference Program Abstract

Gold Sponsors
Nanotech Gold Sponsors
Silver Sponsors
Nanotech Silver Sponsors
Gold Key Sponsors
Nanotech Gold Key Sponsors
Nanotech Ventures Sponsors
Nanotech Ventures Sponsors
Nanotech Sponsors
News Headlines
NSTI Online Community

© Nano Science and Technology Institute, all rights reserved.
Terms of use | Privacy policy | Contact