Nano Science and Technology InstituteNano Science and Technology Institute
Nano Science and Technology Institute 2005 NSTI Nanotechnology Conference & Trade Show
Nanotech 2005
Bio Nano 2005
Business & Investment
Nano Impact Workshop
Index of Authors
Index of Keywords
Keynote Presentations
Confirmed Speakers
Participating Companies
Industry Focus Sessions
Nanotech Expo
Special Symposia
Venue 2005
Press Room
Site Map
Nanotech 2005 At A Glance
Nanotech Proceedings
Nanotechnology Proceedings
Global Partner
nano tech
Supporting Organizations
Nanotech 2005 Supporting Organization
Media Sponsors
Nanotech 2005 Medias Sponsors
Event Contact
696 San Ramon Valley Blvd., Ste. 423
Danville, CA 94526
Ph: (925) 353-5004
Fx: (925) 886-8461

Polymeric Hybrid Microstructures for Smart Targeting and Drug Delivery

A. Dudia, J.S. Kanger and V. Subramaniam
University of Twente, NL

artificial cell, polystyrene microcapsules, nanofabrication, biomimetic

Artificial cells (AC) refer to (sub) micro-vehicles that can perform a specific bio-function in the body, without being rejected from the immune system. Such smart targeting and drug delivery systems are aimed for use in medicine, studying fundamental biological processes, diagnostics, etc. Our approach of a hybrid AC consists of a non-biological and impermeable scaffold (i.e. polystyrene) combined with an artificial lipid membrane where functional bio-molecules will be implemented. Implementation of biomolecular motors such as ATPase is the first goal of our work. Here we report on the fabrication and loading of the scaffold and the functionalization of the AC. Single nanoholes are introduced in the polystyrene micro scaffolds in a controlled way by using a focused ion beam. Hydrophilic solution is loaded in these hydrophobic scaffolds via nanoholes. In addition, artificial bilayer lipid membranes are deposited on a surface in a controlled way by manipulating unilamellar vesicles with optical tweezers and collapsing them on a surface. The thickness of the membrane patch is characterized using atomic force microscopy. In the near future we will functionalize the AC by incorporating biomolecules in the lipid membrane patch that separates the interior of the AC to the surrounding medium.

Back to Program

Sessions Sunday Monday Tuesday Wednesday Thursday Authors

Nanotech 2005 Conference Program Abstract

Gold Sponsors
Nanotech Gold Sponsors
Silver Sponsors
Nanotech Silver Sponsors
Gold Key Sponsors
Nanotech Gold Key Sponsors
Nanotech Ventures Sponsors
Nanotech Ventures Sponsors
Nanotech Sponsors
News Headlines
NSTI Online Community

© Nano Science and Technology Institute, all rights reserved.
Terms of use | Privacy policy | Contact