Nanotech 2004 Tutorial

Fundamentals and Applications of Micro/Nanofluidics

Steve Wereley

Purdue University

This short course will start with a consideration of the fundamentals of intermolecular forces and proceed to a consideration of where continuum assumptions are valid and where they are not. Scaling phenomena will be discussed, i.e. the importance of surface tension and dominance of drag, in continuous flows. The breakdown of continuum behavior will then be discussed and the utility of computational simulations outlined. A short introduction to electrokinetics will be provided. Then experimental techniques suitable for micro/nano flows will be presented. Finally aero-based examples will be discussed.

The short course will encompass issues ranging from nanotechnolgy to microsystems technologies (MEMS).

Topics

1. Fluid mechanics theory in small but continuous flows
2. Sub continuum fluids theory
3. Electrokinetics
4. Microscale experimental diagnostics
5. Aero applications of microfluidics

Outline

1. Introduction
• Intermolecular Forces
• The Three States of Matter
• Continuum Assumption
2. Continuum Fluid Mechanics at Small Scales
• Boundary Conditions
• Low Reynolds Number Flows
• Surface Tension
3. Molecular Approaches
• Molecular Dynamics simulations
• Direct Simulation Monte Carlo Technique
4. Electrokinetics(Electro-Osmosis, Electrophoresis, Dielectrophoresis)
5. Experimental Flow Characterization
• Pointwise Methods
• Full-Field Methods
6. Overview of Micro-PIV
• Fundamental Physics Considerations of Micro-PIV
• Extensions of the Micro-PIV technique
• Microfluidic Nanoscope
• Micro particle Image Thermometry
• Infrared Micro-PIV
• Particle Tracking Velocimetry
7. Application Examples
• Flow in a Microchannel
• Flow in a Micronozzle
• Flow Around a Blood Cell
• Flow in Microfluidic Biochip

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