Nanotech 2014 Vol. 2
Nanotech 2014 Vol. 2
Nanotechnology 2014: MEMS, Fluidics, Bio Systems, Medical, Computational & Photonics

Modeling, Simulation & Informatics Chapter 6

Monte Carlo Simulation of Electrochemical Detection of Redox Molecules with Nanoscale Redoxcycling

Authors: P. Zhu, S. Iwahara, K. Nakazato, and S. Uno

Affilation: Ritsumeikan University, Japan

Pages: 407 - 410

Keywords: redoxcycling, Monte Carlo

Biosensors that can detect minute quantities of important redox molecules in the human body are increasingly gaining attention nowadays. Currently, electrophoresis,fluorescence and amperometric detection methods are the common techniques used for such purpose. The previous two methods require large equipment and long detection time. On the other hand, amperometric detection by nanoscale redoxcycling method is more reliable due to its high sensitivity, rapid response and the ability to conduct microscale sample measurement. Therefore, many works on this method are published.and most of them include simulation to optimize the design and predict the performance of the sensors. In the previous studies, mass transport of analyte molecules is expressed by the diffusion equation.However, in low concentration analtye molecule, the effectiveness of this method has not been proved. In this paper, Monte Carlo simulation of nanoscale redoxcycling is performed, where analtye molecules are expressed by particles. The simulation results show that even in extremely low analyte concentration, the steady-state current is in accord with the result obtained using diffusion equation This suggests that the diffusion equation is applicable to extremely low analyte concentration cases.

ISBN: 978-1-4822-5827-1
Pages: 570
Hardcopy: $209.95