Nano Science and Technology Institute
Nanotech 2014 Vol. 2
Nanotech 2014 Vol. 2
Nanotechnology 2014: MEMS, Fluidics, Bio Systems, Medical, Computational & Photonics
Chapter 4: Bio Nano Materials

Preparation and characterization of starch nanoparticles by desolvation method

Authors:S. Uzun, J.L. Kokini
Affilation:University of Illinois, US
Pages:297 - 300
Keywords:starch nanoparticles, desolvation, biocompatible nanoparticles
Abstract:Nanoparticles prepared from biocompatible and biodegradable materials have attracted considerable attention in food and pharmaceutical science. Starch is one of abundant biopolymer. In this study, starch nanoparticles were produced by desolvation method and the influence of various parameters during desolvation was studied in terms of change in size, zeta potential and morphology of starch nanoparticle. ). Particle size and zeta potential of nanoparticles were determined by Dynamic Light Scattering and morphology of particles was characterized by Scanning Electron Microscopy (SEM). Starch nanoparticles were produced from those starch mixtures in ethanol and larger nanoparticles were obtained from higher amylopectin starch. It was also found that temperature has significant effect on producing very small particles. . By increasing the stirring speed of ethanol from 200 rpm to 800 rpm in controlled environment, progressive increase in particle size was achieved and larger particles were observed in SEM. The stability of starch nanoparticles was improved using 1% surfactant, Sodium dodecyl sulfate (SDS), and particles remained stable for 3 days. The starch-based nanoparticles could be promising tool as carrier for drug delivery
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