Authors: M.A.S. Melo, L. Cheng, K. Zhang, M.D. Weir, L.C. Chow, J.M. Antonucci, N.J. Lin, S. Lin-Gibson, H.H.K. Xu
Affilation: University of Maryland Dental School, United States
Pages: 289 - 292
Keywords: dental material, silver nanoparticles, calcium phosphate nanoparticles
Dental caries is a wide spread public health problem, despite much effort in health promotion. Caries at the margins of restorations has been the main reason for failure. The development of direct-filling dental materials with antibacterial and remineralizing properties is a promising alternative to addressing this problem. Based on nanotechnology, nanoparticles of silver (NAg) and nanoparticles of amorphous calcium phosphate (NACP) were introduced into dental materials to achieve antimicrobial and remineralizing properties, respectively. Dental materials containing NAg were recently reported by our research group. Modified adhesive system components and composite with the addition of NAg achieved great antibacterial effects on oral biofilms using a low NAg filler level., without adversely affecting the dentin bond strength. Previous studies have reported lesion remineralization around novel nanocomposite, which contained NACP. In the present contribution we report the development of a set of restorative materials such as dental primer, adhesive and composites that containing NAg and NACP. The antibacterial, remineralizing and mechanical properties of these new dental materials indicate that novel nano-sized agents provide a new framework for biomaterials that can fight bacteria and reduce the demineralization in restored tooth cavities.