Nanotech 2013 Vol. 3
Nanotech 2013 Vol. 3
Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)

Materials for Drug & Gene Delivery Chapter 3

Reverse Thermoresponsive Polymers for Sustained Delivery of Therapeutic Agents

Authors: R. Mayadunne, A. Balachandra, T. Gunatillake, C. Lindall

Affilation: CSIRO, Australia

Pages: 278 - 280

Keywords: sustained delivery, injectable

Abstract:
CSIRO has developed thermoresponsive polymers for encapsulation and sustianed release of bioactives. They are stable aqueous solutions over 24 months, easily pass through a 25 gauge needle at room temperature and immediately gel into a sustained release depot on in vivo injection. They are designed to be biodegradable and well tolerated in vivo based. Theyare able to deliver therapeutic agents, enzymes/proteins and small molecule drugs over an extended period of time. Additionally, the materials and their components are compendia materials and amenable to existing GMP manufacture.


ISBN: 978-1-4822-0586-2
Pages: 806
Hardcopy: $209.95