Nano Science and Technology Institute
Nanotech 2013 Vol. 3
Nanotech 2013 Vol. 3
Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)
Chapter 3: Materials for Drug & Gene Delivery

Reverse Thermoresponsive Polymers for Sustained Delivery of Therapeutic Agents

Authors:R. Mayadunne, A. Balachandra, T. Gunatillake, C. Lindall
Affilation:CSIRO, AU
Pages:278 - 280
Keywords:sustained delivery, injectable
Abstract:CSIRO has developed thermoresponsive polymers for encapsulation and sustianed release of bioactives. They are stable aqueous solutions over 24 months, easily pass through a 25 gauge needle at room temperature and immediately gel into a sustained release depot on in vivo injection. They are designed to be biodegradable and well tolerated in vivo based. Theyare able to deliver therapeutic agents, enzymes/proteins and small molecule drugs over an extended period of time. Additionally, the materials and their components are compendia materials and amenable to existing GMP manufacture.
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