Nanotech 2013 Vol. 3
Nanotech 2013 Vol. 3
Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)

Bio Nano Materials Chapter 2

A Specific Surface-coating Peptide for Rare Earth Nanomaterials

Authors: Y.J. Zhang, W. Zhou, L.P. Wen

Affilation: University of Science and Technology of China, China

Pages: 210 - 212

Keywords: rare earth nanomaterials, phage display, peptides, cell interaction, biomedical applications

Abstract:
The induction of autophagy on exposure of cells to a variety of nanoparticles represents both a safety concern and an application niche for engineered nanomaterials. Using phage display, we have discovered an 11-amino acid peptide that binds to rare earth nanomaterials with high affinity and forms a stable coating layer on the surface of the nanocrystals. The peptide efficiently reduces sedimentation of the nanocrystals and the interaction of nanocrystals with cells and surfaces, while the addition of a homing peptide enhances the interaction of nanocrystals with the target cells and organs. In this presentation I will present the latest development on utilizing this novel peptide to enable biomedical applications for rare earth nanomaterials and formation of rare earth-based composite nanomaterials.


ISBN: 978-1-4822-0586-2
Pages: 806
Hardcopy: $209.95