Nanotech 2013 Vol. 2
Nanotech 2013 Vol. 2
Nanotechnology 2013: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational (Volume 2)

Inkjet Design, Materials & Fabrication Chapter 4

Bio-ink for inkjet printing of living cells

Authors: C.J. Ferris, K.J. Gilmore, S. Beirne, D. McCallum, G.G. Wallace, M. in het Panhuis

Affilation: ARC Centre of Excellence for Electromaterials Science (ACES), Australia

Pages: 261 - 264

Keywords: cell, inkjet, biomaterials, bio-ink

Abstract:
This abstract summarises our recent work on the development of a bio-ink tailored for the controlled deposition of cells by inkjet printing. Direct printing of living cells is an emerging approach to the fabrication of tissue- or organ-like structures for application in regenerative medicine and in vitro drug screening and toxicology. Significant advances in bio-ink design are needed to continue the progression of this technology towards a clinically relevant biofabrication tool. Particularly, bio-inks for inkjet printing must simultaneously satisfy often disparate engineering and biological requirements, such as preventing cell settling and aggregation whilst retaining printability, without cytotoxic effects. The bio-ink described in this work uses a novel microgel suspension and biocompatible surfactants to achieve the above requirements to enable robust cell deposition from many-nozzle piezoelectric inkjet print heads. We employed this capability to fabricate a range of cell constructs and microarrays. We believe that the bio-ink described in this work is an important advance in inkjet cell printing.


ISBN: 978-1-4822-0584-8
Pages: 808
Hardcopy: $209.95

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