Nano Science and Technology Institute
Nanotech 2013 Vol. 2
Nanotech 2013 Vol. 2
Nanotechnology 2013: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational (Volume 2)
Chapter 4: Inkjet Design, Materials & Fabrication

Bio-ink for inkjet printing of living cells

Authors:C.J. Ferris, K.J. Gilmore, S. Beirne, D. McCallum, G.G. Wallace, M. in het Panhuis
Affilation:ARC Centre of Excellence for Electromaterials Science (ACES), AU
Pages:261 - 264
Keywords:cell, inkjet, biomaterials, bio-ink
Abstract:This abstract summarises our recent work on the development of a bio-ink tailored for the controlled deposition of cells by inkjet printing. Direct printing of living cells is an emerging approach to the fabrication of tissue- or organ-like structures for application in regenerative medicine and in vitro drug screening and toxicology. Significant advances in bio-ink design are needed to continue the progression of this technology towards a clinically relevant biofabrication tool. Particularly, bio-inks for inkjet printing must simultaneously satisfy often disparate engineering and biological requirements, such as preventing cell settling and aggregation whilst retaining printability, without cytotoxic effects. The bio-ink described in this work uses a novel microgel suspension and biocompatible surfactants to achieve the above requirements to enable robust cell deposition from many-nozzle piezoelectric inkjet print heads. We employed this capability to fabricate a range of cell constructs and microarrays. We believe that the bio-ink described in this work is an important advance in inkjet cell printing.
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