Nano Science and Technology Institute
Nanotech 2012 Vol. 3
Nanotech 2012 Vol. 3
Nanotechnology 2012: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)
Chapter 3: Materials for Drug & Gene Delivery

Surfactant Effect on Intercellular Transport of DNA, Proteins, and Electrolytes

Authors:D. Assan, X. Gao, J.C.K. Lai, S.W. Leung
Affilation:Idaho State U, US
Pages:162 - 165
Keywords:surfactant, DNA, enzymes, proteins, electrolytes, transport
Abstract:Surfactants play a key role on bodily functions at molecular level, such as cell signaling and signal transmission. Their importance in cell survival is well recognized, but the surfactant effect on intermolecular/interfacial mass transport is not well understood and the available information of the subject is very limited quantitatively. In this report, we systemically studied the effect of surfactants on intercellular transport of DNA, proteins, and some key electrolytes with an artificial cellular system constructed with a semipermeable membrane. The permeabilities of these biomolecules and electrolytes across the semipermeable membranes in the artificial cell system were measured. Results of this study provide quantitative understanding of intermolecular interfacial mass transport that is important in the design of many fore-coming applications of biotechnology.
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