Nano Science and Technology Institute
Nanotech 2011 Vol. 3
Nanotech 2011 Vol. 3
Nanotechnology 2011: Bio Sensors, Instruments, Medical, Environment and Energy
Chapter 3: Bio Nano Materials

Hybrid bionanomaterials based on nanocrystalline TiO2 and catechol-grafted polymers: the effect of composition and morphology on photo and bioactivity

Authors:F. Cellesi
Affilation:University of Manchester, UK
Pages:279 - 282
Keywords:hybrid bionanomaterials, TiO2 nanoparticles, dopamine, polymer shell
Abstract:We proposed a synthetic strategy for producing hybrid bionanomaterials based on nanocrystalline TiO2 and catechol-grafted polymers. A sol-gel process in organic solvent was developed to grow TiO2 nanocrystals of highly controlled size and surface chemistry, and easily redispersible in water. A bio-inspired approach was then used to graft hydrophilic polymers on the TiO2 nanoparticles, utilising terminal catechol groups as chelating enediol ligands. These polymer-coated nanoparticles showed a safe cytotoxic profile and provide interesting advantages for applications in diagnostics, cell targeting and immunostimulation.
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