Nano Science and Technology Institute
Nanotech 2011 Vol. 3
Nanotech 2011 Vol. 3
Nanotechnology 2011: Bio Sensors, Instruments, Medical, Environment and Energy
Chapter 1: Bio Sensors, Diagnostics, Imaging & Instrumentation

Fabrication of PEG Hydrogel Microstructures in Microfluidic System for Multicellular Spheroid Formation, Culturing and Analysis

Authors:C.-Y. Fu, H.-Y. Chang
Affilation:National Tsing Hua University, TW
Pages:98 - 100
Keywords:microfluidic system, spheroids, PEG hydrogel, bioartificial liver
Abstract:In this abstract, we describe a novel PEG-based, simple-to-fabricate, U-shaped micro-scale growth chamber, which allows cell trapping and forming into spheroids as well as culturing in the presence of a continuous perfusion flow, a long-term 3D cell culture can be achieved. We believe that it can provide a good platform for many liver spheroid-based studies and applications in the future.
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