Nanotech 2011 Vol. 3
Nanotech 2011 Vol. 3
Nanotechnology 2011: Bio Sensors, Instruments, Medical, Environment and Energy

Bio Sensors, Diagnostics, Imaging & Instrumentation Chapter 1

Fabrication of PEG Hydrogel Microstructures in Microfluidic System for Multicellular Spheroid Formation, Culturing and Analysis

Authors: C.-Y. Fu, H.-Y. Chang

Affilation: National Tsing Hua University, Taiwan

Pages: 98 - 100

Keywords: microfluidic system, spheroids, PEG hydrogel, bioartificial liver

Abstract:
In this abstract, we describe a novel PEG-based, simple-to-fabricate, U-shaped micro-scale growth chamber, which allows cell trapping and forming into spheroids as well as culturing in the presence of a continuous perfusion flow, a long-term 3D cell culture can be achieved. We believe that it can provide a good platform for many liver spheroid-based studies and applications in the future.

Fabrication of PEG Hydrogel Microstructures in Microfluidic System for Multicellular Spheroid Formation, Culturing and Analysis

ISBN: 978-1-4398-7138-6
Pages: 852
Hardcopy: $199.95