Nanotech 2011 Vol. 2
Nanotech 2011 Vol. 2
Nanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational

Micro & Nano Fluidics Chapter 7

The Physics of Pressure Powered Micro-Flow Focusing Device for the Encapsulation of Live Cells

Authors: J. Berthier, P. Dalle, F. Rivera, R. Renaudot, S. Morales, P-Y. Benhamou, P. Caillat

Affilation: CEA-Leti, France

Pages: 458 - 461

Keywords: encapsulation, live cells, FFD, flow regime

Abstract:
Flow focusing devices (FFD) have emerged as a powerful tool for cell encapsulation and formation of micro-emulsions [1,2]. In the frame of live cell encapsulation, a micro-FFD using alginate solutions for the capsule and powered by highly controllable pressure pumps has been developed [3,4]. This work deals with the different aspects of the problem: the rheology of alginates, the flow regimes and flow charts, the influence of the different parameters and a scaling analysis. Experimental observations of capsules produced in the microsystem are finally shown.

The Physics of Pressure Powered Micro-Flow Focusing Device for the Encapsulation of Live Cells

ISBN: 978-1-4398-7139-3
Pages: 854
Hardcopy: $199.95