Nano Science and Technology Institute
Nanotech 2011 Vol. 1
Nanotech 2011 Vol. 1
Nanotechnology 2011: Advanced Materials, CNTs, Particles, Films and Composites
 
Chapter 1: Nanoscale Materials Characterization
 

siRNA Delivery Using Biodegradable Nanoparticles for Breast Cancer Therapy

Authors:S. Abbasi, P. Arghya, K. Afshan, S. Prakash
Affilation:McGill University, CA
Pages:74 - 76
Keywords:nanoparticles, biodegradable, siRNA, breast cancer
Abstract:Polyethylenimine (PEI)-coated human serum albumin (HSA) nanoparticles form suitable biocompatible carriers for therapeutic molecules. Small interfering RNA (siRNA) molecules have suggested great promise as a future therapy for breast cancer. In order to overcome the problems of degradation and low cellular transfection associated with siRNA, PEI-HSA nanoparticles are used. These nanoparticles are characterized to allow efficient delivery of siRNA to MCF-7 breast cancer cells.
ISBN:978-1-4398-7142-3
Pages:882
Hardcopy:$199.95
 
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