siRNA Delivery Using Biodegradable Nanoparticles for Breast Cancer Therapy

	Nanotech 2011 Vol. 1 Nanotechnology 2011: Advanced Materials, CNTs, Particles, Films and Composites Chapter 1: Nanoscale Materials Characterization
	siRNA Delivery Using Biodegradable Nanoparticles for Breast Cancer Therapy
Authors:	S. Abbasi, P. Arghya, K. Afshan, S. Prakash
Affilation:	McGill University, CA
Pages:	74 - 76
Keywords:	nanoparticles, biodegradable, siRNA, breast cancer
Abstract:	Polyethylenimine (PEI)-coated human serum albumin (HSA) nanoparticles form suitable biocompatible carriers for therapeutic molecules. Small interfering RNA (siRNA) molecules have suggested great promise as a future therapy for breast cancer. In order to overcome the problems of degradation and low cellular transfection associated with siRNA, PEI-HSA nanoparticles are used. These nanoparticles are characterized to allow efficient delivery of siRNA to MCF-7 breast cancer cells.
ISBN:	978-1-4398-7142-3
Pages:	882
Hardcopy:	$199.95

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