A proof of concept: a model of targeted stealth nanoparticles that are stable and biocompatible for RNA interference in vivo to macrophages

	Nanotech 2010 Vol. 3 Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy Chapter 5: Drug & Gene Delivery
	A proof of concept: a model of targeted stealth nanoparticles that are stable and biocompatible for RNA interference in vivo to macrophages
Authors:	M.S. Yusuf, A.D. Miller, C.H. Prata
Affilation:	Imperial College Gene Therapies Centre, UK
Pages:	364 - 367
Keywords:	liposome, Mannose receptor, siRNA, macrophage
Abstract:	Bringing together advances generated through the developing fields of bionanotechnology and gene therapy, and demonstrated through the ABCD model, we propose a biocompatible, stable, specific stealth lipoplex targeting macrophages, as proof of concept, which is to be developed into a novel disease modifying agent in the treatment of systemic autoimmune diseases such as rheumatoid arthritis
ISBN:	978-1-4398-3415-2
Pages:	880
Hardcopy:	$189.95

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