Authors: C. Mille, R.W. Corkery
Affilation: YKI, Institure for Surface Chemistry, Sweden
Pages: 246 - 249
Keywords: membrane proteins, structural proteins, self assembly, templating, porous material, lipid matrix
Two membrane proteins derived from yeast, Yop1p and Rtn1p, have been engineered, heterogeneously expressed and purified. Both proteins are membrane spanning and can be found in all eukaryotes in which they are used for structural control of the endoplasmatic network. Yop1p and Rtn1p have previously been shown to induce tubules in lipid vesicles and we have seen that by altering the concentration of structuring protein, the vesicle morphology can be controlled. By using the same molecules found in nature, the structure and properties of these biological materials can be mimicked.