Nano Science and Technology Institute
Nanotech 2010 Vol. 3
Nanotech 2010 Vol. 3
Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy
Chapter 3: Nano for Biotech, Interfaces & Tissues

Size of the Pores Created by an Electric Pulse: Microsecond vs Millisecond Pulses

Authors:G. Saulis, R. Saule
Affilation:Vytautas Magnus University, LT
Pages:226 - 229
Keywords:electroporation, pore size, bleomycin, eryhtrocytes, mouse hepatoma cells, CHO
Abstract:Modeling studies have revealed that the pulse of nanosecond-duration should create smaller pores than the pulse of micro-millisecond duration. It can be expected, that similar differences should also exist between the pore populations created by the pulses of micro- and millisecond-durations. Here, we compared the size of the pores created by a square-wave electric pulse with the duration of 100 us and 2 ms. For the cells studied, short 100 us-duration pulse created smaller pores than longer 2 ms-duration pulse
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