Nano Science and Technology Institute
Nanotech 2010 Vol. 3
Nanotech 2010 Vol. 3
Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy
Chapter 1: Bio Sensors, Diagnostics & Imaging

Integrated lab-on-a-chip Influenza diagnostic designed for low cost manufacturing

Authors:A.F. Sauer-Budge, P.L. Mirer, A. Chatterjee, C.M. Klapperich, A. Sharon
Affilation:Fraunhofer USA, US
Pages:54 - 57
Keywords:influenza, lab-on-a-chip, manufacturable
Abstract:In this paper we describe a completely integrated lab- on-a-chip for genetic analysis of bacteria or viruses. The chip was designed for low cost manufacturing in thermoplastics by choice of low cost materials (thermoplastics) and designing for injection molding and for minimal assembly. To reduce the complexity of the disposable chip, all active components were removed from the microfluidic chip and incorporated into an instrument. We present the integrated chip and associated instrument for detection of bacteria and viruses. In particular, here we demonstrate the on-chip RT-PCR and detection using the CDC proprietary assay for influenza A.
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