Nano Science and Technology Institute
Nanotech 2010 Vol. 3
Nanotech 2010 Vol. 3
Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy
Chapter 1: Bio Sensors, Diagnostics & Imaging

Synchrotron radiation microtomography for the ex-vivo and in-vivo evaluation of nanoparticle-labeled stem cell homing in muscular tissue

Authors:F. Fiori, A. Farini, A. Giuliani, A. Manescu, C. Villa, Y. Torrente
Affilation:Polytechnic University of Marche, IT
Pages:81 - 84
Keywords:Duchenne muscular dystrophy, stem cells, synchrotron radiation, microtomography
Abstract:This work was carried out in the frame of a more general research program aiming to use human stem cells to repair muscle damage in Duchenne Muscular Dystrophy. The results of X-ray microtomography experiments, carried out both ex-vivo and in-vivo at the European Synchrotron Radiation Facility are presented. It is shown that the distribution of intra-arterially delivered stem cells can be visualized by microtomography both in muscle biopsies and in living murine models, providing biological insights into the early processes of muscle stem cell homing.
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