Authors: P. Li
Affilation: The Hong Kong Polytechnic University, China
Pages: 917 - 919
Keywords: amphiphilic, core-shell, particle, synthesis
We have developed a novel and commericial viable route to a wide range of highly uniform, amphiphilic core-shell particles in nano- to micro-scaled sizes. Novel feature of this synthetic approach is that it combines graft copolymerization, in situ self-assembly of the resulting amphiphilic graft copolymers and emulsion polymerization in a one-step synthesis. This versatile methodology allows us to design and tailor-made particles for specific applications through selection of appropriate amino-containing water-soluble polymers and hydrophobic monomers. Special features of this synthetic route and products include: - The particles are easy to synthesize in high solid content (up to 30%) without using surfactant. - The particles have well-defined core-shell nanostructure ranging from nano-to micro-scale with narrow particle size distribution. - The process uses aqueous-based Chemistry, which is environmentally benign. - The core properties of the particles can be varied (e.g. hard, soft, temperature-sensitive and hollow). - The shell component can use a wide range of amine containing water-soluble polymers such as synthetic and biopolymers - Surface functionalities and properties can be easily altered. This process offers a commercially viable route to a wide variety of novel core-shell particles with different sizes, compositions, structures and functions. Applications of these unique particles in gene and drug deliveries, enzyme immobilization, bioseparation, water treatment, antibacterial and functional coatings have been demonstrated.