Nano Science and Technology Institute
Nanotech 2009 Vol. 2
Nanotech 2009 Vol. 2
Nanotechnology 2009: Life Sciences, Medicine, Diagnostics, Bio Materials and Composites
Chapter 4: Biosensors and Diagnostics

Relaxation Time Constants of Nanometals in Human Tissues and Clinical Applications

Authors:R. Sharma, A. Sharma
Affilation:Center of Nanotechnology, IN
Pages:243 - 246
Keywords:picotechnology, pico fluorescein spectrometer, HIV, nitric oxide, mercury, lead
Abstract:The metals are in abundance in human body in biofluids, blood, cerebrospinal fluid, saliva, lymph. These metals are found in free and bound forms in each tissue and their amount is tissue specific. The mechanism of major metals and their binding affects their nuclear magnetic resonance relxation times. The longitudinal relaxation (T1) and transverse (T2) time constants are unique signatures in detection and classifying major soft tissue cancers or tissue diseases. We developed a data base of relaxivities of normal and diseased human tissues both soft and solid types. The evaluation of relaxation behavior of major human tissue diseases was made and relaxation time constants of human tissues were measured. The database of tissues is helpful as cheaper technology for quicker tissue characterization. The database also useful in imaging suits as reference guide. In conclusion, database of human tissue tumors and human fluid T1 and T2 relaxation times was developed based on nanometal NMR relaxation signatures.
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