Microparticles on the Basis of Segmented Polyurethanes for the Treatment of Tuberculosis

	Nanotech 2009 Vol. 2 Nanotechnology 2009: Life Sciences, Medicine, Diagnostics, Bio Materials and Composites Chapter 2: Drug Delivery
	Microparticles on the Basis of Segmented Polyurethanes for the Treatment of Tuberculosis
Authors:	E.O. Batyrbekov, R. Iskakov, B. Zhubanov
Affilation:	Institute of Chemical Sciences, KZ
Pages:	96 - 99
Keywords:	microcapsules, polyurethane, tuberculosis
Abstract:	The objective of the research is to develop a new drug delivery system based on polyurethane microparticles for the treatment of tuberculosis by pulmonary administration to the lungs. The synthesis and characterization of polyurethane microcapsules are studied making use three molecular weight poly(ethylene glycol), poly(propylene glycol) and tolylene-2,4-diisocyanate. Antitubercular drugs such as isoniazid, ethionamide or rifampicin were The antitubercular effect of polyurethanes was tested using disc diffusion method against a museum strain of Mycobacterium tuberculosis.incorporated into the polyurethane microcapsules.
ISBN:	978-1-4398-1783-4
Pages:	590
Hardcopy:	$179.95

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