Authors: M. Chung, J.W. Lan, H.Y. Lin, T.W. Suen, S.H. Cheng
Affilation: Southern Taiwan University, Taiwan
Pages: 180 - 182
Keywords: electrospinning, nanoparticle, nanofiber, magnetic
Nanoparticles added into nanofibers produced by electrospinning can expand the functions of such fibers, and these nanoparticles can serve as vehicle for drugs in active drug delivery concept. Depending on the toxicity of these nanoparticles, sometime it is desired to cover them inside a polymer while benign ones exposed in order to contact the cell it is to interact with. We achieve this control of nanoparticle position on electrospun nanofiber with magnetism. Two horizontal magnet is placed at the receptor position, and nonmagnetic, superparamagnetic, and paramagnetic nanoparticles of Ag, Fe3O4 (<20 nm), Fe3O4 (>50 nm) were added inside PVP solutions in electrospinning process. We found the nonmagnetic Ag and superparamagnetic Fe3O4 nanoparticles exist inside the nanofiber, while paramagnetic Fe3O4 nanoparticles exist mainly on the surface of nanofibers. The interaction of the magnetic field and the paramagnetic Fe3O4 nanoparticles at the final stage of nanofiber formation makes this possible.