Nano Science and Technology Institute
Nanotech 2008 Vol. 3
Nanotech 2008 Vol. 3
Nanotechnology 2008: Microsystems, Photonics, Sensors, Fluidics, Modeling, and Simulation - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 3
Chapter 3: Lab-on-a-Chip, Micro & Nano Fluidics

Numerical Analysis of Nanofluidic Sample Preconcentration in Hydrodynamic Flow

Authors:Y. Wang, K. Pant, W. Diffey, Z. Chen, S. Sundaram
Affilation:CFD Research Corporation, US
Pages:442 - 445
Keywords:streaming potential, nanofluidic, electric double layer, preconcentration
Abstract:This paper presents the first, high-fidelity numerical study of nanofluidic streaming potential-based sample preconcentration. Parametric analysis is performed to capture the critical effects of pressure and background electrolyte (BGE) concentration on preconcentrator performance. Our studies demonstrate that ion-polarization and electric field barrier can be established at micro-nano-channel interfaces and substantial sample enrichment (>10,000-fold) can be readily achieved using hydrodynamic flow. The results can be used for practical design and operational protocol development for novel sample preconcentrators.
Numerical Analysis of Nanofluidic Sample Preconcentration in Hydrodynamic FlowView PDF of paper
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