 | Nanotech 2008 Vol. 3
Nanotechnology 2008: Microsystems, Photonics, Sensors, Fluidics, Modeling, and Simulation - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 3
Chapter 3: Lab-on-a-Chip, Micro & Nano Fluidics |
Numerical Analysis of Nanofluidic Sample Preconcentration in Hydrodynamic Flow | |
| Authors: | Y. Wang, K. Pant, W. Diffey, Z. Chen, S. Sundaram |
| Affilation: | CFD Research Corporation, US |
| Pages: | 442 - 445 |
| Keywords: | streaming potential, nanofluidic, electric double layer, preconcentration |
| Abstract: | This paper presents the first, high-fidelity numerical study of nanofluidic streaming potential-based sample preconcentration. Parametric analysis is performed to capture the critical effects of pressure and background electrolyte (BGE) concentration on preconcentrator performance. Our studies demonstrate that ion-polarization and electric field barrier can be established at micro-nano-channel interfaces and substantial sample enrichment (>10,000-fold) can be readily achieved using hydrodynamic flow. The results can be used for practical design and operational protocol development for novel sample preconcentrators. |
| ISBN: | 978-1-4200-8505-1 |
| Pages: | 940 |
| Hardcopy: | $159.95 |
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