Nanotech 2008 Vol. 2
Nanotech 2008 Vol. 2
Nanotechnology 2008: Life Sciences, Medicine & Bio Materials - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 2

Nano Medicine & Neurology Chapter 6

Upconverting nanoparticles for in vitro and in vivo cellular imaging

Authors: D.K. Chatterjee, Y. Zhang

Affilation: National University of Singapore, Singapore

Pages: 535 - 538

Keywords: nanoparticles, upconversion, fluorescence, imaging probes

Abstract:
Conventional fluorescent labels are of limited in vivo utility because short-wavelength radiation penetrates tissues poorly and excites strong background autofluorescence. Upconversion nanoparticles (UCN) convert low-energy exciting photons to visible emissions, resulting in deep tissue penetration and high detection sensitivity in vivo. Here, we report the synthesis and characterization of fluorescent UCN and demonstrate their use in molecular imaging in vitro and in vivo in small animals.

Upconverting nanoparticles for in vitro and in vivo cellular imaging

ISBN: 978-1-4200-8504-4
Pages: 808
Hardcopy: $159.95