Authors: E. Vismara, D. Pizzolato, S. Bertini, G. Torri, A. Valerio
Affilation: Politecnico, Italy
Pages: 487 - 490
Keywords: heparin, cyclodextrin, nanostructure, biological activity
We set up different synthetic approaches to afford new different nanostructures cyclodextrin – low molecular weigh heparin (LMWH) characterized by covalent bonds (amine or amide) between -cyclodextrin and LMWH in different positions of the heparin chain. As far as we know , they are the first examples of this kind of nanostructures. They could sum in one adduct the well-know properties of cyclodextrin and heparin alone and in this direction their potential biological activities will be tested.