Nano Science and Technology Institute
Nanotech 2008 Vol. 2
Nanotech 2008 Vol. 2
Nanotechnology 2008: Life Sciences, Medicine & Bio Materials - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 2
 
Chapter 4: Drug & Gene Delivery Systems
 

Amphoteric liposomes are a platform for multi-organ delivery of oligonucleotides

Authors:C. Reinsch, U. Rauchhaus, S. Panzner
Affilation:novosom AG, DE
Pages:328 - 331
Keywords:siRNA, delivery, in vivo, liposomes
Abstract:Oligonucleotides (ONs) such as antisense (ASO) or siRNA have created a need for new technologies that further enable the systemic and targeted delivery of these active principles. Here, we describe amphoteric, fully charge-reversible liposomes as a novel carrier concept that overcomes the limitations in biodistribution of cationic vectors systems while keeping functionality.
Amphoteric liposomes are a platform for multi-organ delivery of oligonucleotidesView PDF of paper
ISBN:978-1-4200-8504-4
Pages:808
Hardcopy:$159.95
 
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