Nano Science and Technology Institute
Nanotech 2008 Vol. 2
Nanotech 2008 Vol. 2
Nanotechnology 2008: Life Sciences, Medicine & Bio Materials - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 2
 
Chapter 3: Biomarkers, Nano Particles & Materials
 

The Study of the Nanocontact Imprint with Aminosilane

Authors:F.Y. Shen, N.H. Chen, K-Y Lam, J.H. Chen, F-S Huang
Affilation:National Tsing Hua University, TW
Pages:270 - 273
Keywords:contact imprinting, HSQ, Aminosilane, Anti-Mouse protein
Abstract:The purpose of this paper is to develop nano-contact imprint technology with simple process by using soft HSQ (hydrogen silsesquioxane) mold transfer aminosilane ink on HSQ and glass substrates with binding Glutraic dialdehyde (GA) and Affinipure Goat Anti-Mouse igG(H+L) protein sequentially for bio application. HSQ molds were fabricated by low-dose e-beam lithography with various wires width, 80nm~200nm, the ratio of line width and space is 1:10 and 1:1, Aminosilane was used as ink, the nano-features on the HSQ stamps were successfully transferred onto the substrates with strong adhesion under specific conditions in the range of 350~450W O2 plasma treatment for 30 s and 10~35 psi imprinting pressure for 30s. We used AFM to measure the nano line before and after soaking with GA and Anti-Mouse igG(H+L) protein of transfer aminosilane pattern and to observe the protein was absorbed with aminosilane successfully. The layer thickness of GA with protein is about 5 nm. As we know, the size of the Anti-Mouse protein is 5nm*5nm*30nm. This indicates an approximate monolayer of absorbed igG(H+L) protein on the GA bound to patterned aminosilane nano line. Bio application on sensors and facilitate will be investigated further.
The Study of the Nanocontact Imprint with AminosilaneView PDF of paper
ISBN:978-1-4200-8504-4
Pages:808
Hardcopy:$159.95
 
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