Nanotech 2008 Vol. 1
Nanotech 2008 Vol. 1
Nanotechnology 2008: Materials, Fabrication, Particles, and Characterization - Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 1

Nano Materials & Composites Chapter 2

Permeability and protein separations: functional studies of porous nanocrystalline silicon membranes

Authors: J. Snyder, M. Kavalenka, D. Fang, C. Striemer, P. Fauchet, J. McGrath

Affilation: University of Rochester, United States

Pages: 333 - 335

Keywords: nanomembranes, protein separations

Abstract:
We have developed an ultrathin (15nm) freestanding nanoporous silicon based membrane [1]. This new material, termed porous nanocrystalline silicon (pnc-Si), is fabricated using standard photolithography techniques. Pore sizes can be tuned in a thermodynamically driven self-assembly step during pnc-Si manufacture. The intrinsic characteristics of this new material and its relatively facile fabrication make it superior to commercial membranes and other currently studied nanomembranes. Pnc-Si air and water flow rates are an order of magnitude higher than those reported of carbon nanotube membranes and commercial track etched membranes. We have employed pnc-Si membranes in protein separations, and because of the well defined pores, observe sharp molecular weight cutoffs of complex protein mixtures. Additionally we have used pnc-Si membranes to perform blood protein separations, and have observed separations by diffusion alone that are difficult for standard hemodialysis membranes to achieve.

Permeability and protein separations: functional studies of porous nanocrystalline silicon membranes

ISBN: 978-1-4200-8503-7
Pages: 1,118
Hardcopy: $159.95