Nano Science and Technology Institute
Nanotech 2007 Vol. 2
Nanotech 2007 Vol. 2
Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2
 
Chapter 8: Bio Materials and Tissues
 

Using Chondroitin Sulfate to Synthesize Nanoparticles

Authors:K.P. Vercruysse, A. Williams, D. Ivory, B. Johnson, R.D. Dixon, M.T. Tran and J.T. Moore
Affilation:Tennessee State University, US
Pages:752 - 755
Keywords:chondroitin sulfate, glycosaminoglycan, metal nanoparticles
Abstract:We provide evidence that chondroitin sulfate (CS), a member of the glycosaminoglycan (GAG) family of polysaccharides found in the extracellular matrix of all higher order species, can be used as a matrix to generate nanosized gold (Au), silver (Ag), palladium (Pd) and rhodium (Rh) particles. Aqueous solutions containing Au3+, Ag+, Pd2+ or Rh3+ cations were mixed with aqueous solutions containing CS. Nanosized Au or Ag particles were generated without the use of an additional reducing agent following incubation of the mixtures at room temperature for 48 hours. Nanosized Pd or Rh particles were generated at room temperature within 10 minutes following the addition of NaBH4. UV/VIS spectroscopic scans of the samples revealed novel absorption features that were not observed in aqueous samples of CSA or cation alone. In addition, TEM images of the samples confirmed that nanoscale particles had been generated. The images indicate the particles possessed irregular geometries, however some faceting was observed in the Au particles. Preliminary studies, using UV/VIS spectroscopic analyses, suggest that the chemistry described above could be applied using heparin, pectin or carboxymethylcellulose as the matrix, but to a much lesser extent when using hyaluronan as the matrix. In addition, using CS as the matrix and NaBH4 as the reducing agent, novel UV/VIS spectroscopic features emerge when applying the above described chemistry to aqueous solutions containing Cu(II), Ni(II), Pt(IV), Hg(II) or Mn(II) cations.
Using Chondroitin Sulfate to Synthesize NanoparticlesView PDF of paper
ISBN:1-4200-6183-6
Pages:838
Hardcopy:$139.95
 
Order:Mail/Fax Form
Up
© 2014 Nano Science and Technology Institute. All Rights Reserved.
Terms of Use | Privacy Policy | Contact Us | Site Map