Papers:
Preparation of multifuctional nanofibrous scaffold for tissue engineering
Multifucntional fibrous scaffolds can be produced via layer-by-layer deposition of electrospun nanofibers containing variable function. This scaffolds can be used in tissue engineering of complex structure by allowing specific controlled microenvironment for heterogeneous cell types.
Novel surface architectures for biomimetic lipid membranes
Many important biological processes occur at, via or across one of the various lipid membranes present in the cell. These include transport governed by transmembrane proteins constituting more than 50% of all drug targets of [...]
Protons’ binding within nanometer scaled compartments of natural ionic reservoirs: Bacillus subtilis spores
Dormant spores of bacteria of Bacillus genus are intriguing micrometer-scaled objects for a physico-chemical study. The most paradoxical feature of dormant spores is that, being metabolically inactive and resistant to environmental insults, they actually monitor [...]
Favored Osteoblast Interactions with Aerosol Printed 3D Nano-to-Macro Hierarchical Architectures: The Promise of Nanocomposites as Orthopedic Prostheses
Ceramic/polymer nanocomposites simulate bone in terms of its nanostructure and associated properties, thus, offering a promising new opportunity for bone regeneration in a natural way. Previous in vitro studies demonstrated that well-dispersed nanophase titania in [...]
Electrophoretic RNA Transport Through Transmembrane Carbon Nanotubes
We study electrophoretic transport of RNA through carbon nanotubes embedded in membranes using molecular dynamics simulations. % Doped and naked carbon nanotubes are inserted into a dodecane membrane and a dimyristoylphosphatidylcholine lipid bilayer and we [...]
Phage-Derived Bioselective Nanovehicles for Drug and Gene Delivery
Phage display technology rests on two fundamental concepts: combinatorial chemistry and fusion phage. We first demonstrated fusion of the major coat protein of the phage with foreign random peptides, which results in landscape phage libraries. [...]
Protein binding to particle surfaces determines intracellular interaction and uptake kinetics
People are exposed to nanoparticles in from varying sources and in many ways. The goal of our research is to simplify this diverse problem by establishing a systematic understanding of the properties of particles that [...]
Biocompatibilities of some synthetic polymers in films
Materials for artificial devices require biocompatibility with the human body. Moreover, it has been well known that the implants are facilely tainted with pathogenic bacteria during surgical processes and that a few bacteria circulate in [...]
Nanodiamonds for Detoxification
Gibson N., Fitzgerald Z., Luo T.-J., Shenderova O., Grichko V., Bondar V., Puzur A., Brenner D., North Carolina State University, US
Our research deals with using nanodiamond particles as an enterosorbent to remove mycotoxins from the gastrointestinal tract. We are working on developing an ideal enterosorbent by obtaining appropriate size nanoparticles, modify nanodiamond surface groups, and [...]
Nanocomposites for Restorative Dentistry
Dental filling materials are crosslinked resins with high abrasion resistance. Inorganic micro and recently nanofillers are introduced to improve their properties. However, the shrinkage of the resin component during the polymerization reaction is still a [...]
Mechanical Properties of Nano-Structure Controlled Ti-Hf Alloy for Dental Implant
Objectives: Cp-Ti has a excellent biocompatibility. So, it was widely used dental implants and artificial joint. But it is not strong enough for some dental applications. Since Hf belongs to the same group as Ti [...]
Effects of Zr Content on the Electrochemical Characteristics of Nano-Structure Controlled Ti-alloys
Objective: Pure Ti as well as Ti-6Al-4V alloy exhibit excellent properties for dental implant applications. However, for a better biocompatibility it seems important to avoid in the composition the presence of V due to the [...]
Nanotopography-controlled Cell Life and Death
NIH-3T3 cells were grown on nanodot arrays to investigate how cells respond to nanolandscape. The nanodot arrays consisted nanodot of diameters ranging from 10 to 200 nm which were fabricated by AAO processing on Ta-coated [...]
Diffusion of Nanoparticles through the Tissues in Experiment
Reshetov I.V., Frank G.A., Sukharev S.S., Efremov G.D., Danileico Yu.C., Timoshenko V.Yu., P.A.Hertzen Moscow Research Oncological Institute (MROI), RU
We have created nanocrystals of silicon with sizes in the greatest measurement in the average 50 nm (from 4 to 100 nm), and nanocrystals of the oxide of aluminum with the adsorbed molecules of phthalocyanines, [...]
Integration of Living Cells with Silicon Microstructures for MEMS Applications
Molnar P., Bhargava N., Das M., Natarajan A., Wilson K., Hickman J.J., University of Central Florida, US
For many years biological and silicon-based structures were considered incompatible because of the difficulties to engineer an effective interface connecting the two systems. Recent developments in surface chemistry, bioengineering and cell biology enabled the creation [...]
Silicon Dioxide Nanoparticles Can Exert Cytotoxic Effects on Neural Cells
Lai J.C.K., Lai M.B., Lai J.C.K., Lai M.B., Edgley K.L., Bhushan A., Dukhande V., Daniels C.K., Leung S.W., Idaho State University, US
The health risk and cytotoxic effects of nanoparticles are almost unknown. Consequently, we have launched an interdisciplinary research program to systematically investigate the toxicity of nanoparticles. An initial observation prompted us to hypothesize that SiO2 [...]
Nano-Surface Behavior of Osteoblast Cell-Cultured Ti-30(Nb,Ta) with Low Elastic Modulus
Ti and Ti-alloys have good biocompatibility, appropriate mechanical properties and excellent corrosion resistance. However, the widely used Ti-6Al-4V is found to release toxic ions (Al and V) into the body, leading to undesirable long-term effects. [...]
In vitro & in vivo toxicity of CoFe2O4 nanoparticles for application to magnetic hyperthermia
Kim D-H., Kim K-M, Kim K.N., Kim D-H., Kim K-M, Kim K.N., Kim D-H., Kim K-M, Kim K.N., Shim I-B, Lee Y.K., The University of Alabama, Tuscaloosa, US
Magnetic nanoparticles offer some attractive possibilities in biomedicine because it has the special physical properties. So, we can usually consider four particular applications: magnetic separation, drug delivery, hyperthermia treatments and magnetic resonance imaging (MRI) contrast [...]
Using Chondroitin Sulfate to Synthesize Nanoparticles
Vercruysse K.P., Williams A., Ivory D., Johnson B., Dixon R.D., Tran M.T., Moore J.T., Tennessee State University, US
We provide evidence that chondroitin sulfate (CS), a member of the glycosaminoglycan (GAG) family of polysaccharides found in the extracellular matrix of all higher order species, can be used as a matrix to generate nanosized [...]
Electrospun Microfiber Tubes and Self-Assembling Peptides Stimulate Neural Regeneration in Rat Sciatic Nerve Transections
Gelain F., Panseri S., Modica L., Taraballi F., Lowery J., Vescovi A., University of Milan-Bicocca, IT
Peripheral nerve injury is still a traumatic pathology that may impair patient’s movements by interrupting his motor-sensory pathways. New synthetic nerve grafts comprising electrospun tubes and tailored self-assembling peptides are used in our study to [...]
Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 20, 2007
Industry sector: Medical & Biotech
Topic: Biomaterials
ISBN: 1-4200-6183-6