 | Nanotech 2007 Vol. 2
Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2
Chapter 6: Biosensors |
Evaluation of silver nanostructures fabricated using glancing angle depostion as localized surface plasmon resonance biosensors | |
| Authors: | D.A. Gish, F. Nsiah, M.T. McDermott and M.J. Brett |
| Affilation: | University of Alberta, CA |
| Pages: | 461 - 464 |
| Keywords: | localized surface plasmon resonance, glancing angle deposition, biosensor, silver nanostructures |
| Abstract: | The localized surface plasmon resonance (LSPR) biosensing capability of 175 nm thick silver nanoparticle films produced by glancing angle deposition (GLAD) was evaluated. The extinction spectra of the films exhibited a peak around a wavelength of 369 nm which was observed to red-shift linearly with increasing refractive index of the surrounding medium. The films were functionalized with solutions of 11-amino-1-undecanethiol, hydrochloride and rabbit immunoglobulin G (IgG) to allow for the detection of anti-rabbit IgG binding. Binding of biomolecules to the nanoparticle surface increases the local refractive index and results in a red-shifting of the extinction peak. The wavelength shift at varying concentrations of anti-rabbit IgG was measured and fit to the Langmuir isotherm. |
| ISBN: | 1-4200-6183-6 |
| Pages: | 838 |
| Hardcopy: | $139.95 |
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