Nanotech 2007 Vol. 2
Nanotech 2007 Vol. 2
Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2

Biosensors Chapter 6

Evaluation of silver nanostructures fabricated using glancing angle depostion as localized surface plasmon resonance biosensors

Authors: D.A. Gish, F. Nsiah, M.T. McDermott and M.J. Brett

Affilation: University of Alberta, Canada

Pages: 461 - 464

Keywords: localized surface plasmon resonance, glancing angle deposition, biosensor, silver nanostructures

Abstract:
The localized surface plasmon resonance (LSPR) biosensing capability of 175 nm thick silver nanoparticle films produced by glancing angle deposition (GLAD) was evaluated. The extinction spectra of the films exhibited a peak around a wavelength of 369 nm which was observed to red-shift linearly with increasing refractive index of the surrounding medium. The films were functionalized with solutions of 11-amino-1-undecanethiol, hydrochloride and rabbit immunoglobulin G (IgG) to allow for the detection of anti-rabbit IgG binding. Binding of biomolecules to the nanoparticle surface increases the local refractive index and results in a red-shifting of the extinction peak. The wavelength shift at varying concentrations of anti-rabbit IgG was measured and fit to the Langmuir isotherm.

Evaluation of silver nanostructures fabricated using glancing angle depostion as localized surface plasmon resonance biosensors

ISBN: 1-4200-6183-6
Pages: 838
Hardcopy: $139.95