Label-Free Protein Nano-Biosensor Using Top-Down Fabrication

	Nanotech 2007 Vol. 2 Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2 Chapter 6: Biosensors
	Label-Free Protein Nano-Biosensor Using Top-Down Fabrication
Authors:	C.S. Ah, A. Kim, H.Y. Yu, C.-G. Ahn, J.-H. Yang, I.B. Baek, C.W. Park, M.S. Jun and S.J. Lee
Affilation:	Electronics and Telecommunications Research Institute (ETRI), KR
Pages:	493 - 495
Keywords:	Si FET, nanosensor, top-down, PSA, electrical detection, protein
Abstract:	A nanosensor of n-type Si field-effect transistor (FET) via “top-down method” was employed to monitor PSA with great selectivity and high sensitivity up to 10 pg/mL. When a biomaterial, negatively charged PSA, is introduced through a fluidic channel, the conductivity of FET is lowered than that in pure buffer solution from the n-type nature of nanochannel as a bionanosensor. The Si FET bionanosensor allows a real-time monitoring without any labeling, which indicates this electrical property originated from the specific binding between antibody and antigen.
ISBN:	1-4200-6183-6
Pages:	838
Hardcopy:	$139.95

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