Authors: S. Zheng, R. Wang, W. Che, W.J. Harrison, Z. Yang and C. Li
Affilation: Eastman Kodak Company, United States
Pages: 343 - 344
Keywords: nanoparticles, nanoprobe, block copolymers, self-assembly, optical molecular imaging, near infrared
Optical molecular imaging (OMI) is a very powerful tool for studying the temporal and spatial dynamics of specific biomolecules and their interactions in real time in vivo. It exhibits the great advantages of high temporal (picosecond) and spatial (submicron) resolutions, high sensitivity (single-molecule level) and minimal invasion. This presentation focus on the design and synthesis of nanoparticle-based nanoprobes for OMI in near infrared. The nanoparticles are derived from core-crosslinked micelles. In-vitro and in-vivo study of the nanoprobes will be presented as well.