Nano Science and Technology Institute
Nanotech 2006 Vol. 2
Nanotech 2006 Vol. 2
Technical Proceedings of the 2006 NSTI Nanotechnology Conference and Trade Show, Volume 2
Chapter 4: Computational Modeling in Life Sciences

Modelling the Microscopic Mechanisms of Sonoporation

Authors:J.M. Burns, P.A. Prentice, A. Cuschieri and P.A. Campbell
Affilation:University of Dundee, UK
Pages:333 - 336
Keywords:sonoporation model, boundary elements, ultrasound, microjetting, contrast agent, microbubbles
Abstract:This work constitutes a theoretical follow up to our earlier paper in Nature Physics (November 2005) in which we demonstrate that, in the high amplutude limit, ultrasound stimulated microbubble cavitation behaviour can be approximated without the need for a shell parameter, which simplifies matters considerably.
We discuss how a high amplitude threshold arises and validate the coding with our own in-house generated experimental data taken with our unique ultra high speed imaging system.
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