Nano Science and Technology Institute
Nanotech 2006 Vol. 1
Nanotech 2006 Vol. 1
Technical Proceedings of the 2006 NSTI Nanotechnology Conference and Trade Show, Volume 1
 
Chapter 1: Nanoscale Structures and Devices
 

Cell Separation and Manipulation by magnetic field in the presence of functionalised magnetic nanowires

Authors:A. Prina-Mello, Z. Diao and J.M.D. Coey
Affilation:CRANN Research Laboratory, IE
Pages:62 - 63
Keywords:magnetism, nanowires, cell separation, cell alignment,
Abstract:In this paper we investigate the possibility of using magnetic nanowires in cell separation and manipulation. Ni, Co/Cr and Co/Fe nanowires made by electrochemical deposition in anodic aluminum oxide (AAO) templates. The combination between nanowires and different cells such as MC3T3 mouse fibroblasts, UMR-106 has been shown. There, cell viability with all the three kinds (Ni, Co/Cr and Co/Fe) of nanowires after combination was monitored. Magnetic cell separations were carried out following standardized conditions have achieved 75% purity and 75% yield.
Moreover, we were also successful in aligning the nanowires with cells in a 0.1 T uniform magnetic field. There, the axial of the magnetic nanowires internalised into cells can be aligned to the field direction with uniform magnetic field.
Therefore, a cell-nanowire interaction and living study will be addressed in the future in order to understand the intrinsic mechanisms responsible for cell internalization and alignment.
Cell Separation and Manipulation by magnetic field in the presence of functionalised magnetic nanowiresView PDF of paper
ISBN:0-9767985-6-5
Pages:871
Hardcopy:$119.95
 
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